Equilibrium and Release Properties of Aqueous Dispersions of Non Steroidal Antiinflammatory Drugs Complexed with Polyelectrolyte Eudragit E 100

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Equilibrium and Release Properties of Aqueous Dispersions of Non-Steroidal Anti-Inflammatory Drugs Complexed with Polyelectrolyte Eudragit E 100

Equilibria and release properties of aqueous systems consisting of a set of five non-steroidal anti-inflammatory drugs (AH) complexed with the cationic polymethacrylate Eudragit E 100 (EU) are reported in this study. The composition (EU(AH)(50) (HCl)(50)) having fifty mole percent of each counterion (A(-) and Cl(-)) produces clear, stable aqueous dispersions in which a remarkably high proportio...

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ژورنال

عنوان ژورنال: Scientia Pharmaceutica

سال: 2012

ISSN: 0036-8709,2218-0532

DOI: 10.3797/scipharm.1107-17